宝鸡地区儿童腺病毒感染现状分析

Analysis on adenovirus infection status of children in Baoji area

目的:了解腺病毒3、7血清型在呼吸道感染患儿中的感染情况,并进行流行病学分析,为临床提供诊断和治疗依据。方法:随机收集宝鸡市妇幼保健院儿童医院儿科2015年11月(22例)和2016年3月(48例)腺病毒Ig M抗体检测阳性的患儿血清标本共70例,用ELISA方法进行腺病毒3、7型血清学检测,依据患儿的年龄、性别、发病季节和感染部位进行流行病学分析。结果:冬季22例,3、7型均阳性;春季48例,3型2/48为阳性,7型48/48为阳性。男性患儿41例,女性患儿29例;≤1岁患儿42例,大于1岁患儿28例;下呼吸道感染53例;上呼吸道感染12例,其他5例。结论:腺病毒3、7型的感染与季节有关,该地区冬季以3、7型混合感染为主,春季以7型感染为主,感染年龄主要为≤1岁的婴幼儿。

Objective： To find out 3,7- type adenovirus infection in children with respiratory tract infections and to conduct epidemiological analysis,so as to provide the basis for clinical diagnosis and treatment. Methods： Random collection of 70 cases from Baoji Maternal and Child Health Hospital of Pediatrics in November 2015（22 cases） and March 2016 Serum（48 cases） Adenovirus Ig M antibody positive samples,which were detected by ELISA method and analysis based on children＇s age,sex,onset seasons and the site of infection epidemiological. Results： Winter 22 cases were all positive for 3,7- type,spring 48 cases,2 cases were positive for type 3,type 7 were all positive. In this group,41 cases were male and 29 were female; less than or equal to 1- year- old children were 42 cases,28 cases of children greater than 1- year- old; lower respiratory tract infection were 53 cases; 12 cases of upper respiratory tract infection,the other were five cases. Conclusion： The 3,7- type adenovirus infection are related to seasons. In winter,the region 3,7based type mixed infection,in spring mainly 7 type infection,infection mainly aged less than or equal to 1- year- old infants.