不同氮量全胃肠外营养支持在脓毒症中的应用效果

Effect of Different Nitrogen of Total Parenteral Nutrition Support in the Application of Sepsis

目的探讨在脓毒症患者中应用不同含氮量的全胃肠外营养支持的价值。方法选取我院收治的80例脓毒症患者,平均分为低氮量组和高氮量组,对比两组营养支持前后的血生化指标、氮平衡和血气指标。结果营养支持后,两组血生化指标(TB、GPT、GOT、BUN、Cr)、氮平衡及血气指标(PaO_2、PaCO_2)比较差异均有统计学意义(P均<0.05)。结论在对脓毒症患者进行营养支持的过程中,干预的起点应为低氮量营养支持,然后再结合患者自身消耗情况调整营养支持方案,可以适当地提高含氮量,在此过程中,需要高度重视对患者各器官功能指标的全面监测,尤其是肺功能和肾功能,以便及时地发现存在的肺、肾功能衰竭等情况,及时地调整营养干预方案,确保患者的生命安全与健康。

Objective To explore the value of different nitrogen of total parenteral nutrition support in the application of patients withsepsis. Methods 80 cases of patients with sepsis admitted to our hospital were selected and equally divided into low nitrogen group and highnitrogen group. The blood biochemical indicators, nitrogen balance and blood gas indicators were compared between two groups before andafter nutritional support. Results After nutritional support, the blood biochemical indicators （TB, GPT, GOT, BUN, Cr）, nitrogen balanceand blood gas indicators （PaO2, PaCO2） had statistical differences between two groups （all P 〈0.05）. Conclusions During the process ofnutrition support in patients with sepsis, the starting point of intervention should be low nitrogen nutrition support. Then the nutrition supportscheme can be adjusted combining with the consumption of patients. It means that the nitrogen content can appropriately increase. In thisprocess, comprehensive monitoring on the function of each organ index of patients need to be attached great importance, especially the lungfunction and renal function, so as to timely find the lung or kidney failure and adjust the nutrition intervention program for ensuring patients＇life safety and health.