阿奇霉素联合红霉素治疗小儿支原体肺炎的临床疗效研究

Study on the Effect of Azithromycin Combined with Erythromycin in the Treating Children with Mycoplasma Pneumonia

目的探讨阿奇霉素联合红霉素治疗小儿支原体肺炎的临床疗效。方法选取我院2014年1月至2016年3月间收治的小儿支原体肺炎患儿80例,随机将其分为两组各40例。对照组采用阿奇霉素治疗,观察组采用阿奇霉素联合红霉素短程序贯治疗。观察两组患儿的疗效。结果治疗后,观察组的总有效率为97.50%,显著高于对照组的80.00%,差异有统计学意义(P<0.05)。观察组的平均退热天数、平均止咳天数和平均住院天数均显著少于对照组,差异有统计学意义(P<0.05);两组的不良反应发生率比较差异无统计学意义(P>0.05)。结论阿奇霉素联合红霉素短程序贯治疗小儿支原体肺炎,能较快地控制肺部症状,有效缩短住院时间,值得临床推广应用。

Objective To explore the clinical effect of azithromycin combined with erythromycin in the treatment of children withmycoplasma pneumonia. Methods 80 cases of children with mycoplasma pneumonia admitted to our hospital from January 2014 to March2016 were selected and divided into two groups, with 40 cases in each group. The control group was treated with azithromycin, while theobservation group received short-range sequential treatment of azithromycin combined with erythromycin. The curative effect of children intwo groups was observed. Results After treatment, the total effective rate of observation group was 97.50%, significantly higher than 80.00%of control group, with statistical difference （P 〈0.05）. The average defervescence days, average cough-relieving days and averagehospitalization days of observation group were significantly fewer than those of control group, with statistical differences （P 〈0.05）. Nostatistical difference was found in the incidence of adverse reactions between two groups （P〉0.05）. Conclusions The short-range sequentialtreatment of azithromycin combined with erythromycin in children with mycoplasma pneumonia can quickly control the pulmonarysymptoms and shorten the hospital time, which is worthy of clinical application and promotion.