摘要
猪繁殖与呼吸综合征(porcine reproductive and respiratory syndrome,PRRS)是由猪繁殖与呼吸综合征病毒(Porcine reproductive and respiratory syndrome virus,PRRSV)引起的一种以导致怀孕母猪流产和仔猪呼吸困难为主要特征的疾病,PRRS已给养猪业造成巨大的经济损失。微RNA(miRNA)是一类重要的转录后调控基因表达的微小RNA分子,广泛存在于各种生物体内。文章综述了miRNA-23、miRNA-26、miRNA-29、miRNA-125、miRNA-181、miRNA-506对PRRSV在猪肺泡巨噬细胞(porcine alveolar macrophages,PAM)或非洲绿猴肾上皮细胞(african green monkey kidney epithelial cell line,Marc-145)中复制的调控作用。
Porcine reproductive and respiratory syndrome （PRRS） is a disease caused by porcine reproductive and respiratory syndrome virus （ PRRSV）, which is characterized by abortion in pregnant sows and breathing difficulty in piglets, causes huge economic losses to the swine in- dustry. MicreRNAs （miRNAs） are a class of small RNA molecules that are important for post - transcriptional regulation of gene expression, and are widely found in various organisms. This paper reviews the regulation effects of miRNA - 23, miRNA - 26, miRNA - 29, miRNA - 125, miRNA - 181 and miRNA -506 on PRRSV proliferation in porcine pulmonary alveolar macrophage ceils （PAMs） or African green mon- key kidney epithelial cell line （Marc -145 ）.
出处
《黑龙江畜牧兽医》
CAS
北大核心
2017年第1期77-79,82,共4页
Heilongjiang Animal Science And veterinary Medicine
基金
国家自然科学基金项目(31460662)
