吸烟者过敏性鼻炎发病风险分析

Analysis of the Risks of Allergic Rhinitis in Smokers

【目的】通过分析SCI上发表的吸烟者过敏性鼻炎发病风险关系的研究，得出吸烟者与过敏性鼻炎发病风险的询证医学证据。【方法】检索MEDLINE、PUBMED、EMBASE、WOS、2004-2015年相关文献，JADA评分评估所涉及研究的质量，取得或者计算出所涉及的相关研究的RR、95％可信期间，综合分析吸烟者过敏性鼻炎发病风险关系。【结果】吸烟者过敏性鼻炎发病风险关系相对于非吸烟风险如下：①吸烟者VS不吸烟者：RR=1．11，95％CI（1．09，1．21），P=0．00，差别有统计学意义；②主动吸烟者VS不吸烟者：RR=1．04，95％CI（1．00，1．09），P=0．038，差别无统计学意义；③被动吸烟者VS不吸烟者：RR=1．12，95％CI（1．10，1．13），P=0．00，差别有统计学意义。【结论】主动及被动吸烟者过敏鼻炎风险都会增加。

[Objective] To study the medical evidence of the related risks on smokers and allergic rhinitis by analyzing the published SCI study involved. [Methods] Relevant literature on MEDLINE, PUBMED, EMBASE, WOS （ 2004 2015） were retrieved , and the quality of the study involved was evaluated by the JADA score so as to aquire or calculate the relevant research involved in the RR, 950% credible period. The relationship between the risk of allergic rhinitis in smokers was comprehensively analyzed.[Results]The risk of allergic rhinitis in smokers was as follows compared with that of non-smokers： 1. Smokers Vs non-smokers： RR=l,11, 95%CI （1.09, 1.21）, P =0.00, the difference was statistically significant; 2. Active smokers vs non-smokers： RR= 1.04, 95 %CI （1, 1.09）, P = 0.038, the difference was not statistically significant;3. Passive smokers vs non-smokers： RR=1.12, 95%CI （1.10, 1.13）, P =0.00, the difference was statistically significant.[Conclusion] Both active and passive smokers will increase the risk of allergic rhinitis.