血液化验在急性感染性发热患者诊断中的应用研究

Application of Blood Test in Diagnosis of Patients with Acute Infectious Fever

目的探讨血液化验在急性感染性发热患者诊断中的应用。方法选取2013年1月—2015年1月该院门诊收治的急性感染性发热患者60例,其中细菌感染44例,病毒感染16例,对所有的患者均采用血清C-反应蛋白检查、血清降钙素原检测联合血常规检查,比较联合检测与单纯血常规检查法、血清降钙素原检测以及血清C-反应蛋白检查检测细菌性感染结果的准确性。结果血清C-反应蛋白检查阳性确诊率为56.7%,血清降钙素原检测检出阳性确诊率为55.0%,血常规检出阳性确诊率为51.7%,联合检测检出阳性确诊率为81.7%,联合检查明显高于3个单一检查的确诊率;采用血清C-反应蛋白检查、血常规检查以及血清降钙素检测,细菌感染患者的各项指标均明显高于病毒感染患者,细菌感染患者和病毒感染患者的检查水平比较差异有统计学意义(P<0.05)。结论血清C-反应蛋白检查、血清降钙素原检测以及血常规检测都可以作为细菌感染性疾病的血清标志物,将3种方法联合检测在急性感染性发热患者的诊断中具有重要的临床意义,值得临床推广使用。

Objective To explore the application of blood test in the diagnosis of acute infectious fever.Methods From January 2013 to January 2015 in our hospital outpatient acute infection fever 60 patients were selected,including bacterial infection in 44 cases,16 cases of virus infection,of all patients are used serum C-reactive protein,serum procalcitonin detection combined blood routine ex-amination and comparison combined detection and single pure blood routine test,serum calcitonin fibrinogen detection and serum Creactive protein（CRP） were examined for the detection of bacterial infection results accuracy.Results Serum C-reactive protein test positive diagnosis rate was 56.7%,serum calcitonin peptide detection positive diagnosis rate was 55.0%,blood routine detection con-firmed positive rate was 51.7%.Combined detection detection confirmed positive rate was 81.7%,joint inspection was significantly higher than that of the three single examination diagnosis rate;mining with serum C-reactive protein test,blood routine examination and serum calcitonin test,bacterial infection indicators of patients were significantly higher than those of patients with viral infections,bacterial infection patients and HIV infected patients with checking the level has significant difference,the difference between the two groups has statistical significance（P 〈 0.05）.Conclusion Calcitonin serum C-reactive protein,serum fibrinogen detection level of rou-tine blood test can be as a bacterial infection disease serum markers,combined detection of three methods in the diagnosis of acute infectious fever patients has important clinical significance,which is worthy of clinical use.