Whooley两问题工具对孕期抑郁情绪筛查性能分析

Anaysis on screening performance of Whooley two-problem tool for depressive emotion during pregnancy

目的分析Whooley两问题工具在我国临床孕妇抑郁情绪常规筛查的使用性能。方法以我国常用的爱丁堡产后抑郁量表、医院焦虑抑郁量表的测评结果为依据,分析Whooley两问题工具的灵敏度、特异度、阳性预测率、阴性预测率、Kappa一致性检验和ROC曲线下面积,探讨其在我国孕妇中的使用性能。结果根据不同筛查评估工具,孕期抑郁发生率为5.3%~29.0%,Whooley两问题工具的灵敏度在31.9%~68.6%,特异度在89.3%~93.8%,阳性预测率在26.4%~68.1%,阴性预测率在77.3%~98.1%,而一致性程度在0.302~0.440,ROC曲线下面积在0.628~0.789。结论我国孕期妇女的抑郁发生率较高,而Whooley两问题工具在我国临床孕期抑郁筛查的性能尚不能被肯定。

Objective To analyze the performance of Whooley two-problem tool for domestic depressive emotion screening of clinical pregnancy. Method Analyze the sensitivity, specificity, positive predictive rate, negative predictive rate, Kappa identity test and area under ROC curve of Whooley two-problem tool based on the results of Edingburgh Postnatal Depression Scale and Hospital Anxiety and Depression Scale （HADS） which are widely used in China. Study on the screening performance for pregnant women in China. Result Incidence of antenatal depression is 5.3%-29.0% based on different evaluation tools. Sensitivity of Whooley two-problem tool is 31.9%-68.6%. Specificity is 89.3%-93.8%. Positive predictive rate is 26.4%-68.1%. Negative predictive rate is 77.3%-98.1%. Result of kappa identity test is 0.302-0.440. Area under ROC curve is 0.628-43.789. Conclusion There is a high incidence of antenatal depression in China. Performance Of Whooley two-problem tool for domestic depressive emotion screening of clinical pregnancy is not certain right now.