相关临床因素对临床Ⅰ期舌鳞癌淋巴结转移的影响

Effect of clinical factors on lymph mode metastasis in cN_0 tongue squamous cell carcinoma

目的探讨相关临床因素对临床Ⅰ期(cN_0期)舌癌的淋巴结转移的影响。方法选择104例cN_0期舌鳞癌患者,分析隐匿性淋巴结转移率及术后1年远期淋巴结转移率与性别、年龄、肿瘤分期、病理分化及术前检查方法之间的关系。结果不同年龄段的术后1年远期淋巴结转移率,不同病理分化及术前检查方法的隐匿性淋巴结转移率与术后1年远期淋巴结转移率之间差异有统计学意义。结论随着年龄的增长,其远期转移率也会增高,分化程度越低的cN_0期舌癌患者其隐匿性淋巴结转移率及1年远期转移率也越高,术前对cN_0期舌癌患者行MRI检查,能有效降低隐匿性淋巴结转移率及1年远期转移率。

Objective To investigate the effect of clinical factors on lymph node metastasis in cN0 tongue squamous cell carcinoma. Methods Totally 104 cases of cN0 tongue squamous cell carcinoma patients were chosen to analyze the effect of gender,age,tumor stage,histological differentiation and preoperative examination methods on occult lymph node metastasis rate and postoperative 1-year forward rate of lymph node metastasis.Results As for occult lymph node metastasis rate,there were significant differences in groups of age,histological differentiation and preoperative examination methods.And as for postoperative 1-year forward lymph node metastasis rate there were significant differences in histological differentiation and preoperative examination methods.Conclusions The forward lymph node metastasis rate is growing with age.And the lower the degree of differentiation of cN0 tongue squamous cell carcinoma patients,the higher rate of its occult lymph node metastasis and 1-year forward lymph node metastasis.Preoperative MRI can effectively reduce the occult lymph node metastasis rate and 1-year forward metastasis rate of cN0 tongue squamous cell carcinoma patients.