聚乙烯醇-壳聚糖复合海绵的制备及性能

Synthesis and Properties of Polyvinyl Alcohol-Chitosan Composite Sponges

为了进一步提高聚乙烯醇-壳聚糖复合海绵的性能,在聚乙烯醇与甲醛的缩醛化反应过程中加入壳聚糖,并使其与其他原料反应制备聚乙烯醇-壳聚糖复合海绵.分别改变配方中发泡剂和壳聚糖的含量,合成了一系列组分不同的聚乙烯醇-壳聚糖复合海绵,研究了发泡剂含量和壳聚糖含量对复合海绵结构、吸水能力和膨胀率的影响,并采用扫描电子显微镜对复合海绵的结构与微观形貌进行表征,测试了改性海绵对大肠杆菌和金黄色葡萄球菌的免疫能力.研究结果表明,选用曲拉通X-405作为发泡剂,当壳聚糖含量为聚乙烯醇质量的10%时,所制备的复合海绵效果最佳,复合海绵具有明显的蜂窝状多孔结构,其吸水率可达到858%.抗菌实验证明,与纯的聚乙烯醇海绵相比,复合海绵对金黄色葡萄球菌具有较好的免疫能力.

To improve the properties of polyvinyl alcohol-chitosan composite sponge, polyvinyl alcohol （PVA） sponge modified by chitosan （PVF-CS） was prepared by adding chitosan powder during the acetalation reaction of PVA and formaldehyde. A series of PVF-CS composite sponges with different composition were prepared by changing the content of vesicant and ehitosan. The effects of the content of vesicant and chitosan on the pore morphology, water absorbability, absorbed speed of water and swelling degree were studied. Moreover, the Scanning Electron Microscopy was carried out to characterize the structure and morphology of the as-prepared sponge. The antibacterial abilities to Escheriehia coli and Staphylococcus aureus were tested. The result indicates the as-prepared sponge possesses the optimal property when Triton X-405 is used as vesicant and the mass ratio of chitosan/PVA is 10%, and the water absorbability of the composite sponge with honeycomb porous scaffold can reach 858%. The antibacterial experiments show that the antibacterial ability of PVF-CS to the Staphylococcus aureus is better than that of pure PVA sponge.