摘要
1.Introduction In Alzheimer’s disease(AD),β-amyloid deposition and neurofibrilla y tangles(NFTs),composed of hyperphosphorylated tau fibrils are considered to be major pathologic features.Evidence from the genetic studies of familial AD has given rise to theβ-amyloid hypothesis in whichβ-amyloid is proposed as the cause of AD;
1.Introduction In Alzheimer’s disease(AD),β-amyloid deposition and neurofibrilla y tangles(NFTs),composed of hyperphosphorylated tau fibrils are considered to be major pathologic features.Evidence from the genetic studies of familial AD has given rise to theβ-amyloid hypothesis in whichβ-amyloid is proposed as the cause of AD;thus,the reduction ofβ-amyloid has been