伴感染性低血钾性麻痹的系统分析

Systematic analysis of concomitant-infectious hypokalemic paralysis

目的 探讨感染与低血钾性麻痹之间的关系及其临床特点。方法 对本组 34例及国内文献报道的 1 1 5例低血钾性麻痹的病例进行感染过程、临床表现、血钾、肌酶、电生理及病毒学检测结果的系统分析。结果 发现各类报道病例间的临床表现及对本病的命名不一致 ,病毒感染缺乏确切依据。本病的典型表现为在感染过程中发生的四肢急性迟缓性瘫痪 ,伴低血钾 ,无神经系统其他损害的表现 ,预后良好 ,多数不再复发。结论 目前尚缺乏足够证据确定本病为一独立的疾病单元。命名以“伴感染性低血钾性麻痹”较为恰当。可能是一组有遗传易感基础 。

Objective To study the relationship between infection and hypokalemic paralysis and its clinical features.Methods A systemic analysis was made on the infection courses,clinical manifestations, serum levels of potassium and creatine phosphokinase,the results of electrophysiological and virological examinations in present 34 patients and 115 cases reported in literature with hypokalemic paralysis.Results There were differences in the clinical manifestations and denominations among the present and reported cases. No definite evidences for virus infections were found among patients who were characterized by acute flaccid paralysis accompanied with hypokalemia in the infection curses. The prognosis of the disorder was better after the patients were given potassium, and most of them didn't recur.Conclusion No enough evidences showed that this disorder was an independent disease.It should be named as 'concomitant infectious hypokalemic paralysis' appropriately. It was probably a syndrome accompanied by infection on the base of hereditary susceptibility.