支原体感染不孕不育女性患者治疗依从性相关因素调查及干预

Related factors of treatment compliance and intervention among infertile women with mycoplasma infection

目的探讨支原体感染的不孕不育女性患者治疗依从性的相关影响因素,然后采用不同的干预方法,从而提高疗效。方法使用自制调查问卷现场调查了2013年1—12月在杭州市第一人民医院生殖医学中心就诊的263例泌尿生殖道支原体属培养阳性的不孕不育女性患者。按依从性的不同,分为完全依从性组(91例)和不稳定依从性组(172例)。调查问卷包括一般人口学资料、婚姻家庭生育情况、支原体检查治疗情况以及支原体感染相关知识知晓情况。并针对影响因素采取个性化的措施及规范化的健康教育,同时进行统计分析。结果 2组在一般人口学资料和支原体感染相关知识知晓情况方面差异有统计学意义(P<0.05)。完全依从性组32~34岁年龄段治疗依从性最好,随着不孕不育年限的增加,依从性下降。文化程度高,在城市中居住,经济收入高的人群对于支原体感染与不孕不育相关知识的需求和知晓率均较高,其治疗的依从性相对较高。治疗方案复杂,医疗费用过高,疾病相关知识缺乏,交流沟通不畅,负性心理因素是影响治疗依从性的重要原因。结论提高支原体感染的不孕不育女性患者的治疗依从性,应从心理学、社会学、护理学、生殖医学相结合的角度形成个性化、规范化、系统化的干预体系。

Objective To investigate the related factors of treatment compliance among infertile women with mycoplasma infection and take the corresponding intervention measures to improve the curative efficacy. Methods By using a self- made questionnaire,the survey was carried out among 263 female patients who get the positive result in genitourinary my- coplasma culture in our hospital between January,2013 and December,2013. According to the treatment compliance, they were divided into full compliance group （91 cases）and unstable compliance group （172 cases）. The items of questionnaire included general demographic information, marriage and family situation, examination and treatment on mycoplasma and infection related knowledge level. The personalized measures and standardized health education were performed according to the influencing factors. The results were analyzed by statistical methods. Results There were significant differences in general demographic data and mycoplasma infection related knowledge between the two groups （ P 〈 0.05 ）. Thirty-two to thirty-four age-groups in the full compliance group showed the best treatment compliance, and the compliance declined with the duration of infertility. The urban population with high education level and income showed increased demand my- coplasma infection and infertility related knowledge and highly awareness rate, whereas lower treatment compliance. The complex treatment, high medical costs, lack of disease knowledge, poor communication and negative psychological factors were the important factors that affected the treatment compliance. Conclusion In order to improve the treatment compliance of infertile women with mycoplasma infection, a personalized, standardized and systematic intervention system should be established combined with psychology, sociology, nursing and reproductive medicine.