穴位埋线对单纯性肥胖患者外周血瘦素及胰岛素的影响

Effect of Acupoint Thread Embedding on the Peripheral Serum Leptin and Insulin Levels in Simple Obesity Patients

目的通过观察穴位埋线对单纯性肥胖患者外周血瘦素及胰岛素的影响,进一步探讨其治疗单纯性肥胖的作用机制。方法将120例单纯性肥胖患者随机分为对照组、电针组、埋线组,每组40例。对照组采用饮食配合运动干预疗法;电针组在对照组的基础上采用电针治疗;埋线组在对照组的基础上采用穴位埋线治疗。治疗2个疗程后,观察3组治疗前后血清瘦素、胰岛素水平的变化情况,并比较3组临床疗效。结果埋线组总有效率为87.5%,电针组为85.0%,对照组为47.5%。埋线组和电针组总有效率与对照组比较,差异均具有统计学意义(P<0.05)。埋线组和电针组治疗后空腹血清瘦素及胰岛素水平与同组治疗前比较,差异均具有统计学意义(P<0.01)。埋线组和电针组治疗后空腹血清瘦素及胰岛素水平与对照组比较,差异均具有统计学意义(P<0.01,P<0.05)。埋线组治疗后胰岛素水平优于电针组,两组比较差异具有统计学意义(P<0.05)。结论穴位埋线是一种治疗单纯性肥胖的有效方法 ,能降低患者空腹外周血清瘦素及胰岛素水平。

Objective To observe the clinical efficacy of acupoint thread embedding on the peripheral serum leptin and insulin levels in simple obesity patients, and to further explore the mechanism of acupoint thread embedding in treating simple obesity. Method A total of 120 patients with simple obesity were randomized into a control group, an eletroacupuncture （EA） group and a thread embedding group, 40 cases in each group. The control group was intervened by diet plus exercise intervention, the EA group by EA treatment in addition to the intervention given to the control group and the thread embedding group by acupoint thread embedding treatment in addition to the intervention given to the control group. The levels of blood serum leptin and insulin in the three groups were observed before and after 2 treatment courses and the clinical efficacies were compared among the three groups. Result The total effective rate was 87.5% in the thread embedding group, 85.0% in the EA group, and 47.5% in the control group. The total effective rates in the thread embedding group and EA group were significantly different from the rate in the control group （P〈 0.05）. The levels of the fasting serum leptin and insulin were significantly changed in the thread embedding group and EA group after the treatment （P〈0.01）. After the treatment, the levels of the fasting serum leptin and insulin in the thread embedding group and EA group were significantly different from those in the control group （P〈0.0I,P〈0.05）. The insulin level in the thread embedding group was better than that in the EA group, and the difference was statistically significant （P〈0.05）. Conclusion Acupoint thread embedding is an effective approach for simple obesity, and it can down-regulate the fasting peripheral serum leptin and insulin levels.