愈胃汤治疗慢性萎缩性胃炎脾虚气滞型临床研究

Clinical Study of Using Yuwei Decoction in the Treatment of Spleen-deficiency and Qi-stagnation Syndrome Type Chronic Atrophic Gastritis

目的:观察"愈胃汤"治疗脾虚气滞型CAG的临床疗效与安全性。方法:随机将60例CAG患者分为治疗组和对照组,并观察临床症状、心电图、胃镜疗效、粪血尿常规、肝肾功能等指标的变化。结果:治疗组和对照组的总有效率分别为86.7%和83.3%,组间比较无统计学意义(P>0.05);治疗组治疗后症状体征总积分明显低于对照组(P<0.05);两组患者抗HP疗效、胃镜,病理结果治疗前后有明显改善(P<0.05),但组间无显著差异(P>0.05);治疗组不良反应发生率显著低于对照组(P<0.05)。结论:"愈胃汤"是治疗CAG脾虚气滞型安全有效的方药。

Objective： To observe the clinical effect and safety of Yuwei Decoction in the treatment of spleen-deficiency and Qi-stagnation type CAG. Methods： 60 cases of CAG were randomly divided into treatment group and controlled group,and the changes of clinical symptoms,ECG,gastroscopy efficacy,fecal hematuria,liver and kidney function and other indicators were observed. Results： the total effective rate was 86. 7% and 83. 3% respectively of the treatment group and the controlled group,had no statistical significance（ P〉0. 05）; after treatment,the symptoms and signs of the total score was significantly lower than that of the controlled group（ P〈0. 05）; two groups of patients with anti HP efficacy,endoscopy,pathology results before and after the treatment was improved significantly（ P〈0. 05）,but there was no significant difference（ P〉0. 05） between the groups;adverse reaction in the treatment group occurred was significantly lower than that of the controlled group（ P〈0. 05）. Conclusion：Yuwei Decoction is safe and effective on treating spleen-deficiency and Qi-stagnation type CAG.