PedsQL^(TM)4.0及RQLQ量表在变应性鼻炎患儿生活质量测定中的应用比较

Comparison of PedsQL^(TM)4.0 and RQLQ scales in the assessment of the quality of life in children with allergic rhinitis

目的:采用对照研究的方法,探讨用PedsQL^(TM)4.0普适性核心量表(简称PedsQL^(TM)4.0)、鼻炎相关生活质量问卷(RQLQ)对变应性鼻炎(AR)患儿进行生活质量测定的效果。方法:通过前瞻性对照设计,用PedsQL^(TM)4.0及RQLQ量表对71例AR患儿、68例慢性咽炎(CP)患儿及62例健康儿童进行生活质量的调查和分析。结果:①PedsQL^(TM)4.0调查显示:AR患儿在社交功能、学校表现2个维度的得分(82.8±19.7、64.0±24.6)较健康儿童(86.2±18.58、4.9±18.7)低(P<0.05),但AR患儿在生理、情感功能2个维度的得分(88.3±20.3、75.4±22.4)与CP患儿相应得分(89.1±17.7、75.9±22.0)相近;②RQLQ调查显示,AR患儿的鼻部症状与实际问题2个维度得分(2.54±1.37、2.70±1.29)最高;③PedsQL^(TM)4.0与RQLQ相关性分析提示,2个量表各维度呈弱相关(r=-0.199^-0.468,P<0.05)。结论:PedsQL^(TM)4.0与RQLQ均可以评价AR患儿生活质量的不同方面,两者结合能够更全面、准确地评价AR患儿的生活质量。

Objective：To explore the value of PedsQL^TM4.0 and RQLQ scales in assessment of quality of life（QOL）in children with allergic rhinitis（AR）.Method：A prospective trial was conducted to survey the QOL status of 71 AR clinical patients,68 chronic pharyngitis（CP）clinical patients and 62 healthy individuals by generic questionnaire PedsQL^TM4.0 and disease-specific questionnaire rhinoconjunetivitis quality of life questionnaire（RQLQ）respectively.The correlation between PedsQL^TM4.0 and RQLQ were analyzed.All the results were analyzed statistically.Result：①By the assessment of PedsQL^TM4.0 the scores of Social functioning and School functioning domains in AR clinical patients（±s,the same as follow.the scores were 82.8±19.7,64.0±24.6 respectively）were less than those（86.2±18.58,4.9±18.7）in healthy individuals（P〈0.05）;while the scores of Physical health and Emotional functioning domains in AR clinical patients（88.3±20.3,75.4±22.4 respectively）were similar with those（89.1±17.7,75.9±22.0）in CP clinical patients（P〉0.05）.②By the assessment of RQLQ in AR patients,the nasal symptom and practical problem domains got the highest scores（2.54±1.37,2.70±1.29 respectively）.③According to the assessment of the correlation between PedsQL^TM4.0 and RQLQ,the correlation was weak（r=-0.199--0.468,P〈0.05）.Conclusion：Both PedsQL^TM4.0 and RQLQ were suitable for assessing the health status of AR clinical patients.PedsQL^TM4.0 and RQLQ each covers different aspectsof the QOL of AR clinical patients,and the combination of the two questionnaires could improve the QOL assessment.