臂丛神经损伤神经移位术后脑运动功能区变化的fMRI研究进展

The fMRI research progress on motor cortex reorganization after brachial plexus injury and nerve transfer

臂丛神经损伤影响上肢运动功能,主要治疗方法为神经移位术,恢复神经通路连续性,近年来健侧C7神经移位术的疗效显著。作者对近年国内外臂丛神经损伤神经移位术治疗、特别是健侧C7神经移位术后任务态和静息态f MRI的研究进行综述,总结大脑运动功能区变化的规律和可能的机制,以对将来的研究和临床工作提供线索。

Brachial plexus avulsion injury （BPAI） is the most severe peripheral nerve injury and typical results in the affected upper limb paralysed, which can be treated by nerve transfer to regain continuity. Nowadays, contralateral C7 nerve transfer has significant effect. According to the task-state and resting-state fMRI studies on brachial plexus injury after nerve transfer, especially contralateral C7 nerve transfer, we think that the change of cerebral motor cortex may follow certain regularity and mechanism. The regularity and mechanism may take a good effect on future research and clinical work.