4-叔丁基苯酚的清洁生产工艺

A Cleaner Production Process of 4-tert-Butyl Phenol

针对目前工业化生产4-叔丁基苯酚存在的不足,以苯酚和叔丁醇为原料,以Fe3+改性的活性黏土为催化剂,探索4-叔丁基苯酚的清洁生产工艺.考察了各种因素对该反应的影响,通过工艺条件优化,确定较佳的工艺条件为:FeCl3和活性黏土的质量比为3∶1,催化剂用量为原料的1.72%(质量分数),苯酚和叔丁醇的摩尔比为6∶1,反应温度为110℃,反应时间为90min.在此反应条件下,4-叔丁基苯酚的收率可达70%以上.催化剂重复套用5次后,依然保持原有的催化活性及对4-叔丁基苯酚的高选择性.

Due to deficiencies in the industrialization of the 4-tert-butyl phenol （4-TBP）,a cleaner production process of 4-TBP was studied using activated clay modified by Fe3＋ as catalyst,and phenol and tert-butanol as raw materials.Factors influencing the pro- duction process were investigated to obtain the optimal conditions.The yield of the target product was above 70% under the optimum conditions as follows：the mass ratio of anhydrous FeCI3 to activated clay was 3：1,the amount of the catalyst was 1.72G （by mass） of the raw materials, the mole ratio of the phenol to tert-butanol was 6：1, the reaction temperature was 110 ℃, and the reaction time was 90 rain.For recyclability,the results showed that the catalyst was still maintained at the original activity and high selectivity for the target product after five cycles.