数字钼靶X线摄影联合MRI动态增强扫描对含钙化灶乳腺良恶性病变的诊断价值

Diagnostic value of digital mammography X-ray and contrast-enhanced MR imaging in distinguishing benign and malignant breast lesions containing calcification

目的 :探讨数字钼靶X线摄影联合MRI动态增强扫描(DCE-MRI)对含钙化灶乳腺良恶性病变的诊断价值。方法 :回顾性分析60例含钙化灶乳腺病变患者,均行数字钼靶X线摄影及乳腺DCE-MRI检查,并与术后病理结果对照,分别计算数字钼靶X线摄影、DCE-MRI及两者联合诊断乳腺良恶性病变的敏感度、特异度及准确度。结果:本组中良性35例共40个病灶,恶性25例共28个病灶。数字钼靶X线摄影、DCE-MRI及两者联合鉴别乳腺良恶性病变的敏感度分别为71.43%、92.86%、96.43%,特异度分别为77.50%、92.50%、95.00%,准确度分别为75.00%、92.65%、95.59%。结论:数字钼靶X线摄影联合DCE-MRI对含钙化灶乳腺良恶性病变的鉴别诊断具有一定价值。

Objective：To compare the effectiveness of digital mammography X-ray,DCE-MRI in the detection and diagnosis of breast cancer and to assess the value of these modalities as well as the combination of two. Methods：Sixty patients with surgery and pathology proved breast lesion （benign,n=40;malignant,n=28） underwent digital mammography X-ray,DCE-MRI. Of the results of these two modalities,all lesions were classified into 5 groups according to BI-RADS classification. The sensitivity and specificity of each modality as well as the combination of the two were calculated. Results：This study included 35 patients with 40 benign malignant breast lesions and 28 patients with malignant malignant breast lesions. The sensitivities of the digital mammography X-ray,DCE-MRI and the combination of two in differential diagnosis of benign and malignant breast lesions are 71.43% ,92.86% ,96.43% respectively;the specificity are 77.50% ,92.50% ,95.00% respectively and the accuracy are 75.00%, 92.65% ,95.59% respectively. Conclusion：The combination of digital mammography X-ray and contrast-enhanced MR imaging have a certain value of calcifications in the differential diagnosis of benign and malignant breast lesions.