多不饱和脂肪酸与骨质疏松症的相关性

Correlation of polyunsaturated fatty acids and osteoporosis

骨质疏松症是一种常见的老年性代谢骨病。骨质疏松症的发病与年龄、性别、遗传、内分泌、药物、营养等因素相关,但确切的病因及发病机制尚不清楚。近年来越来越多的研究发现骨质疏松症与血脂紊乱相关,而血脂中的脂肪酸影响骨质疏松症的发生和发展,尤其是其中的多不饱和脂肪酸与骨质疏松症关系密切,但其具体机制还不明确。本文就多不饱和脂肪酸与骨质疏松症的相关性作一综述。

Osteoporosis is a common metabolic bone disease in the elderly. The onset of osteoporosis is associated with age, sex, genetics, endocrine, medicine, nutrition and other related factors, but the exact etiology and pathogenesis is still unclear. In recent years, a growing number of studies found that blood lipid disorders were associated with osteoporosis, and the fatty acids in the blood lipid also affected the occurrence and development of osteoporosis. The relationship between osteoporosis and polyunsaturated fatty acids is close, but the specific mechanism is not clear. This paper aims to review the correlation of polyunsaturated fatty acids and osteoporosis.