无创冷冻融脂临床疗效及安全性评估

Clinical efficacy and safety evaluation of non-invasive selective cryolipolysis

目的 评价无创冷冻融脂的临床疗效及安全性。 方法 收集2014年4—10月首都医科大学附属北京安贞医院收治的16例无创冷冻融脂受试者，在治疗前、治疗后3个 月行治疗部位磁共振扫描，记录包括脂肪含量百分比、脂肪厚度等影像学数据及其他非影像学的主客观评价数据，对无创冷冻融脂的疗效和安全性进行评价。 结果 治疗有效 率评价，医生评价为81.2%（13/16），受试者自评为75.0%（12/16），二者差异无统计学意义（P〉0.05）。治疗后治疗区脂肪厚度明显低于治疗前，差异有统计学意义［（2.3± 0.4）cm比（3.0±0.5）cm］（P〈0.01）；治疗前后治疗部位脂肪含量百分比差异无统计学意义（P〉0.05）。无严重不良反应发生。 结论 无创冷冻融脂能安全、有效地减少皮 下脂肪厚度，达到减脂塑形的目的。

Objective To evaluate the clinical efficacy and safety of non-invasive selective cryolipolysis. Methods A total of 16 patients who had non-invasive selective cryolipolysis from April 2014 to October 2014 in Beijing Anzhen Hospital, Capital Medical University were enrolled. Magnetic resonance scan was performed before and 3 months after treatment to record fat percentage and thickness. The effective rate of treatment and adverse reactions were analyzed.ResultsThe subjective effective rate was 81.2%（13/16） and the objective effective rate was 75.0%（12/16）, the difference was not significant（P〉 0.05）. The fat thickness after treatment was significantly decreased compared to that before treatment[（2.3±0.4）cm vs （3.0±0.5）cm]（P〈0.01）. There was no significant difference of fat percentage before and after treatment（P〉0.05）. No severe adverse events were observed. Conclusion Non-invasive cryolipolysis can effectively reduce the subcutaneous fat thickness with good safety.