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尿激酶、白介素-2胸腔灌注联合TP方案治疗肺癌胸腔积液

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摘要 目的:观察尿激酶、白介素-2胸腔灌注联合TP方案治疗肺癌胸腔积液的疗效。方法:将60例肺癌胸腔积液的患者随机分为治疗组30例和对照组30例。对照组单纯给予胸腔置管引流术联合静脉应用紫杉醇和顺铂方案(TP方案)治疗,治疗组胸腔置管引流术联合静脉TP方案化疗同时给予尿激酶、白介素-2胸腔灌注治疗。结果:治疗组有效率为83.3%,高于对照组的60.0%,差异有统计学意义(P<0.05)。治疗组无1例出现包裹性胸腔积液和中心静脉导管堵塞、出血情况,对照组出现包裹性积液2例,导管堵塞4例。治疗组不良反应发生率略高于对照组,差异无统计学意义(P>0.05)。结论:尿激酶、白介素-2胸腔内灌注联合TP方案治疗肺癌恶性胸腔积液安全有效。
出处 《医学理论与实践》 2017年第2期219-220,共2页 The Journal of Medical Theory and Practice
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