摘要
特发性肺间质纤维化,是一种原因不明的以普通间质性肺炎为改变的慢性、弥漫性肺间质疾病。因其发病机制复杂,病情呈不可逆性进展,早期诊断困难,目前亦无有效的临床治疗措施且预后极差,其发病机制成为国内外研究的热点。主要从细胞、细胞因子等方面对近几年特发性肺间质纤维化的发病机制予以综述,或可促进机制的进一步研究,及对精准治疗有所裨益。
Idiopathic interstitial pulmonary fibrosis (IPF) is an unknown-cause ordinary interstitial pneumonia change as chronic and diffuse interstitial lung disease. Because of its complex pathogenesis,irreversible condition progress and early diagnosis difficult for it as well,there is no effective clinical treatment of it,and it has very bad prognosis,therefore,its pathogenesis mechanism has become a hot research at domestic and abroad. The pathogenesis of idiopathic interstitial pulmonary fibrosis is reviewed this paper focuses on the pathogenesis of IPF from the cells,cytokines and other aspects of the pathogenesis of recent years researches,author believe that with the depth study,the pathogenesis of IPF in the future will become increasingly clear,might be promoted its further study,and which help to exactly treatment of this disease.
出处
《实用医药杂志》
2017年第1期72-75,79,共5页
Practical Journal of Medicine & Pharmacy
关键词
特发性肺间质纤维化
发病机制
研究进展
Idiopathic interstitial pulmonary fibrosis
Pathogenesis mechanism
Research progress