摘要
目的通过检测维吾尔族、汉族糖尿病患者凝血指标水平,分析不同民族糖尿病与凝血指标的关系,探讨影响糖尿病患者凝血功能的因素,为糖尿病的预防和治疗提供参考依据。方法收集2014年2月至2015年4月该院确诊为糖尿病患者2 100例为病例组,选择同期体检健康者446例为健康对照组,比较病例组与健康对照组之间凝血指标水平的差异。将不同民族(维吾尔族、汉族)糖尿病患者凝血指标水平进行比较。结果病例组与健康对照组凝血指标水平比较显示,病例组活化部分凝血活酶时间低于健康对照组,差异有统计学意义(P<0.05);病例组纤维蛋白原水平高于健康对照组,差异有统计学意义(P<0.05);病例组与健康对照组之间凝血酶原时间比较差异无统计学意义(P>0.05)。维吾尔族与汉族在病例组凝血指标水平比较显示,维吾尔族活化部分凝血活酶时间低于汉族,差异有统计学意义(P<0.05);维吾尔族纤维蛋白原水平高于汉族,差异有统计学意义(P<0.05);维吾尔族与汉族之间凝血酶原时间比较差异无统计学意义(P>0.05)。结论糖尿病患者凝血功能不同于健康人,糖尿病患者凝血指标水平在不同民族间有所区别。
Objective To explore the changes of coagulation factors in Xinjiang Uygur and Han patients with diabetic mellitus in order to provide reference for the prevention and treatment of diabetic mellitus patients.Methods 2 100 patients with diabetic mellitus were taken as the patient group which were diagnosed in our hospital between February 2014 and April 2015,another 446 healthy people were collected as the control group.The difference of coagulation between diabetic mellitus group and control group was compared.Coagulation between Uygur and Han was compared for 2 100 diabetic mellitus patients.Results The APTT of diabetic mellitus group were significantly less than that in control group(P〈0.05).FIB of diabetic mellitus group were significantly higher than that in control group(P〈0.05).The difference of PT between diabetic mellitus group and control group were not significant(P〉0.05).The APTT of Uygur group were significantly less than Han group(P〈0.05).FIB of Uygur group were significantly higher than Han group(P〈0.05).PT between Uygur group and Han group was not significant(P〈0.05).Conclusion Factors were difference of diabetic mellitus patients and healthy people,coagulation factors in diabetic mellitus patients of Xinjang Uygur and Han.
作者
赵建梅
荣海燕
朱有森
ZHAO J ianmei RONG Haiyan ZHU Yousen(The Medical Laboratory Center of the First Affiliated Hospital of Xinjiang Medical University ,Urumqi ,Xinjiang 830011 ,China)
出处
《国际检验医学杂志》
CAS
2017年第2期187-188,共2页
International Journal of Laboratory Medicine