嗜酸性肉芽肿性多血管炎的临床与胸部影像特征

Radiological and Clinical Features of Eosinophilic Granulomatosis with Polyangiitis

嗜酸性肉芽肿性多血管炎(EGPA)是抗中性粒细胞胞浆抗体相关性小血管炎及高嗜酸粒细胞综合征的一种,以哮喘、浸润性坏死性血管炎、血管外肉芽肿、外周血嗜酸粒细胞增多和多器官组织嗜酸粒细胞浸润为特征。EGPA临床罕见,本文就该病的临床、病理特征及胸部影像特点进行综述。

Eosinophilic granulomatosis with polyangiitis（ EGPA）,also known as Churg-Strauss syndrome,is a clinically rare small-vessel vasculitis associated with antineutrophil cytoplasmic antibodies（ ANCAs）and the hypereosinophilic syndromes（ HESs）, characterized by asthma, disseminated necrotizing vasculitis,extravascular granulomas,peripheral eosinophilia,and tissue eosinophilia.This article reviews the pathology,imaging,and clinical features of EGPA.