重症急性胰腺炎合并腹内高压的临床治疗及观察

The clinical observation and treatment of intra-abdominal hypertension due to severe acute pancreatitis

目的:探讨重症急性胰腺炎合并腹内高压的临床治疗。方法:选取收治的重症急性胰腺炎合并腹内高压患者176例作为本次研究的对象,将患者随机分成对照组与研究组,对照组予以常规治疗,研究组在对照组基础上采用乌司他丁治疗。结果:治疗后研究组患者的IAP、DAO、Ig A、IL-6以及TNF-α水平改善情况要明显优于对照组与治疗前;研究组临床总有效率是97.73%,对照组临床总有效率是79.55%,组间临床疗效对比具有显著性差异。结论:重症急性胰腺炎合并腹内高压患者在常规治疗基础上辅以乌司他丁治疗,能够明显改善腹内高压,提高临床疗效,值得在临床上大力推广。

Objective To investigate the clinical treatment of severe acute pancreatitis complicated with intra-abdominal hypertension. Method 176 cases of patients with severe acute pancreatitis complicated with intra-abdominal hypertension were selected as the research object,The patients were randomly divided into a control group,the study group and the control group were given conventional treatment,research group with UTI treatment in the control group basis. Results After treatment the level of IAP,DAO,Ig A,IL-6 and TNF alpha in the treatment group was improved significantly better than the control group and treatment before; The total effective rate was 97. 73%,the total effectiveness of control group was 79. 55%,clinical curative effect comparison between groups had significant difference. Conclusion Severe acute pancreatitis patients with intra-abdominal pressure on the basis of conventional treatment with ulinastatin treatment,can significantly improve internal high pressure,improve the clinical curative effect,is worth promoting in clinic.