兰索拉唑联合莫沙必利治疗反流性食管炎疗效观察

The curative effect observation of Lansoprazole combined with mosapride in treatment of reflux esophagitis

目的:探讨兰索拉唑联合莫沙必利治疗反流性食管炎临床效果。方法:选择100例反流性食管炎患者,随机分为观察组和对照组。观察组给予兰索拉唑和莫沙必利联合治疗。对照组给予雷尼替丁和莫沙必利联合治疗。评定两组临床疗效和胃镜疗效。结果:观察组临床疗效总有效率(94.0%)高于对照组临床疗效总有效率(80.0%),差异有统计学意义(P<0.05)。观察组胃镜疗效总有效率(92.0%)高于对照组胃镜疗效总有效率(78.0%),差异有统计学意义(P<0.05)。结论:兰索拉唑联合莫沙必利在反流性食管炎治疗中临床和胃镜效果均显著,值得借鉴。

Objective To explore the clinical effect of lansoprazole combined with mosapride in the treatment of reflux esophagitis. Method 100 patients with reflux esophagitis were selected and randomly divided into observation group and control group. The observation group was given lansoprazole and Mosapride treatment. The control group was given mosapride and ranitidine combined treatment. The clinical efficacy and endoscopic efficacy of the two groups was evaluated. Results The total effective rate of clinical efficacy in the observation group（94. 0%） was higher than that in the control group（80. 0%）,the difference was statistically significant（P〈0. 05）. The total effective rateof endoscopic efficacy in the observation group（92. 0%） was higher than that in the control group（78. 0%）,the difference was statistically significant（P〈0. 05）. Conclusion Lansoprazole combined with mosapride in reflux esophagitis treatment has significantly clinical efficacy and endoscopic efficacy,which is worth learning from.