灸法治疗脑卒中后痉挛性偏瘫随机对照试验系统评价

Systematic Review of Randomization Controlled Trials on Moxibustion for Spastic Paralysis after Stroke Patients

目的:通过系统评价和meta分析的方法评价灸法治疗脑卒中后痉挛性偏瘫的疗效和安全性。方法:检索Pubmed、Cochrane图书馆、AMED、中国生物医学文献数据库(CBM)、中文期刊全文数据库(CNKI)等8个数据库至2015年6月止已发表的文献。纳入灸法治疗脑卒中后痉挛性偏瘫的随机对照试验。按照资料提取表提取资料,根据Cochrane协作网推荐的偏倚风险评估方法对纳入文献进行风险评估,用Revman 5.3软件进行数据分析。结果:最终纳入11篇文献,765例患者。meta分析结果显示灸法在改善痉挛状态、提高运动功能和日常生活活动能力等方面有临床疗效,不良反应较少,安全性好。结论:灸法可改善脑卒中后痉挛性偏瘫患者的痉挛状态,提高运动功能和日常生活活动能力,且安全性较高。受纳入研究数量和质量限制,上述结论尚需开展更多大样本、高质量的RCT加以验证。

Objective：A systematic reviewvia review the relevant literature was conducted to assess the therapeutic effect and safety of moxibustion for spastic paralysis after stroke patients. Methods：Published literatures,till June 2015,in Chinese and English,on moxibustion treating spastic paralysis after stroke patients,were searched from Pubmed,CENTRAL（OVID）,CINAHL,Web of Science,AMED,CNKI,Wang Fang databases,CBMweb,etc. Randomize controlled trials（RCTs）on the therapeutic effect of moxibustion for spastic paralysis after stroke patients were included. The data were extracted according to the Table of Data Extraction. The methodological quality of the included literatures was evaluated according to the methods recommended by the Cochrane Collaboration. The data were analyzed with Revman 5.3 software. Results：Totally 11 literatures of RCTs including 765 patients met the inclusion criterion. The results of meta-analysis showed that,moxibustion can relieve spasm and improve the motion ability and the activity of daily life. The moxibustion has little adverse events,and it is safety for spastic paralysis after stroke patients. Conclusion：Moxibustion can relieve spasm and improve the motion ability and the activity of daily life,and it is safety for spastic paralysis after stroke patients. However,due to the limitation of quantity and quality of the included studies,the aforementioned conclusion should be further confirmed by conducting more largescale high-quality RCTs.