临床药师对Ⅰ类切口围手术期患者干预前后预防用抗菌药物的效果分析

Analysis on Efficacy of Prevention with Antibacterial Drugs by Pharmacists Before and after Intervention in Type Ⅰ Incision Perioperative Patients

目的:分析临床药师对I类切口围手术期患者预防用抗菌药物的干预效果,为合理使用抗菌药物提供参考。方法:选取2015年7—12月间医院外科I类切口手术患者296例作为对照组;另选2016年3—8月间I类切口手术患者210例作为干预组,比较两组患者预防用抗菌药物的使用率、合理率及抗菌药物使用平均费用。结果:干预组患者抗菌药物使用率为24.29%低于对照组为88.18%(P<0.05),使用合理率为83.40%高于对照组为56.18%(P<0.05);抗菌药物使用平均费用为(768.00±42.00)元低于对照组为(1 526.00±78.00)元(P<0.05)。结论:通过临床药师干预,能够有效降低外科I类切口围手术期患者抗菌药物的使用率,提高外科I类切口围手术期抗菌药物使用的合理性,降低患者的药品费用,促进了临床抗菌药物的合理使用。

Objective： To analyze the clinical efficacy of prevention with antibacterial drugs by clinical pharmacists before and after intervention in type I incision perioperative patients, and to provide reference for rational use of antimicrobial agents. Methods： Choosing the hospital surgical patients with type l incision operation 296 cases as control group between July 2015 and December 2015. An alternate 210 patients with type I incision operation as intervention group in March 2016 to August, compared two groups of prevention in the use of antimicrobial drugs, rationality and antimicrobial drug use average cost. Results： Patients in antimicrobial drug use intervention group were 24.29% lower than the control group which was 88.18%（P〈0.05）, rational rate was 83.40% higher than the control group which was 56.18% （P〈0.05）; antimJcrobial drug use average cost was （768.00±42.00） yuan RMB lower than the control group （1 526.00±78.00） yuan RMB（P〈0.05）. Conclusion：Throught clinical pharmacists intervention, it can effectively reduce the surgical type I incision raise perioperative antibiotic drug usage, improve perioperative surgical type I incision, the rationality of the application of antibacterial drugs, reduce the patients＇ drug costs, and promote the clinical rational use of antimicrobial drugs.