重复经颅磁刺激与改良电休克治疗首发抑郁症起效时间的临床分析

Clinical Analysis of Onset Time of Repetitive Transcranial Magnetic Stimulation and Modified Electroconvulsive Therapy in First-Episode Depression

目的探讨重复经颅磁刺激与改良电休克治疗首发抑郁症起效时间的临床疗效。方法选取我院2014年7月~2016年2月诊治的首发抑郁症患者中抽取80例作研究对象,经随机抽签方式分组,治疗组（n=40）采取重复经颅磁刺激治疗,对照组（n=40）实行改良电休克治疗,对比两组患者临床疗效与起效时间。结果治疗组患者的治疗总有效率是97.50%,平均起效时间是（9.66±2.54）d;对照组患者的治疗总有效率是80.00%,平均起效时间是（15.48±3.04）d,两组对比差异均有统计学意义（P〈0.05或P〈0.01）。结论重复经颅磁刺激治疗首发抑郁症起效时间的临床疗效更佳,且起效快。

Objective To explore the clinical effect of repetitive transcranial magnetic stimulation（TMR） and modified electroconvulsive therapy（EFS） on onset time of first episode depression. Methods Eighty subjects were recruited from July 2014 to February 2016,who were treated with randomized ballot. The patients in treatment group（n=40） were treated with repeated transcranial magnetic stimulation,and the control group（n=40） were treated with modified electroconvulsive therapy. The clinical curative effect and the onset time were compared between the two groups. Results The total effective rate was 97.50%,the average onset time was（9.66±2.54）d. The total effective rate was 80.00% and the mean onset time was（15.48±3.04）d in the control group. There was significant difference between the two groups（P〈0.05 or P〈0.01）. Conclusion Repeated transcranial magnetic stimulation has a better clinical effect on the onset time of first episode depression,and its effect is quick and can be generalized.