阿托伐他汀钙联合氨氯地平治疗冠心病患者临床疗效观察

Clinical Observation of Atorvastatin Calcium Combined With Amlodipine in the Treatment of Patients With Coronary Heart Disease

目的探究阿托伐他汀钙联合氨氯地平治疗冠心病患者临床疗效。方法选择我院82例冠心病患者随机进行分组,各41例。对照组予以氨氯地平治疗,在此基础上观察组联合阿托伐他汀钙治疗,两组均连续治疗1个月。统计对比两组治疗后总有效率与不良反应发生率。结果经治疗,两组总有效率比较,观察组(95.12%)高于对照组(78.05%),差异具有统计学意义(P<0.05);两组不良反应发生率相比,差异无统计学意义(P>0.05)。结论冠心病患者应用阿托伐他汀钙与氨氯地平联合治疗可提高治疗效果,且安全性较高。

Objective To explore the clinical efficacy of atorvastatin calcium combined with amlodipine in the treatment of patients with coronary heart disease. Methods 82 patients with coronary heart disease were randomly divided into two groups,each with a total of 41 cases. The control group was treated with amlodipine,on this basis,the observation group was treated with atorvastatin calcium,two groups were treated continuously for 1 months. The total effective rate and the incidence of adverse reactions were compared between the two groups after treatment. Results After treatment,the total efficiency of two groups,the observation group（95.12%） was higher than the control group（78.05%）,the difference was statistically significant（P〈0.05）,the adverse effects of the two groups compared,the difference was not statistically significant（P〉0.05）. Conclusion Theapplication of atorvastatin calcium combined with amlodipine in patients with coronary heart disease can improve the therapeutic effect,and the safety is high.