穴位注射结合头针治疗儿童孤独症疗效观察

Clinical observation point injection combined with head acupuncture for children with autism

目的观察穴位注射鼠神经生长因子（mNGF）结合头针治疗儿童孤独症的临床疗效。方法59例24~60个月孤独症患儿按就医时间并在家长知情同意的前提下分为3组。常规康复训练组15例,常规康复训练＋头针治疗组22例,常规康复训练＋头针＋穴位注射治疗组22例。通过治疗前后孤独症行为量表（ABC）、儿童期孤独症评定量表（CARS）、图片词汇量表（PPVT）对患者进行评定。结果常规康复训练＋头针治疗组和常规康复训练＋头针＋穴位注射治疗组均能显著降低ABC总分、CARS得分,提高PPVT评分,差异有统计学意义（P〈0.05）。常规康复训练＋头针＋穴位注射治疗组的治疗效果优于常规康复训练＋头针治疗组,差异有统计学意义（P〈0.05）。结论穴位注射mNGF结合头针治疗2~5岁孤独症患儿疗效显著。

Objective To investigate the effect of point injection of mouse nerve growth factor （mNGF） combined with head acupuncture in treatment of children with autism. Methods A total of 59 cases of children with autism aged 24-60 months,were divided into 3 groups according to the time of hospital visit and under the permission of parents：conventional rehabilitation training group（group A, 15 cases） ,conventional rehabilitation training＋ head acupuncture group（group B, 22 cases） ; conventional rehabilitation＋ head acupuncture＋ point injection group（group C, 22 cases）. The children were evaluated by ABC and CARS and PPVT scales before and after treatment. Results ABC score and CARS score were significantly decreased while PPVT score was increased in group B and C,the difference being statistically significant（P~ 0. 05）. The treatment effect was better in group C than in group B, the difference being statistically significant（P〈0. 05）. Conclusion Point injection of mNGF combined with head acupuncture and simple head acupuncture are both effective for 2-5-year old children with autism,but the effect of the former is better than the latter.