新生儿呼吸衰竭机械通气撤离后预防拔管失败的临床研究

Clinical Study on the Prevention of Extubation Failure After Weaning From Mechanical Ventilation in Neonates With Respiratory Failure

目的 探究新生儿呼吸衰竭机械通气撤离后预防拔管失败的有效方式。方法 选择2012年1月-2016年9月呼吸衰竭新生儿30例为研究对象,将其分为两组,每组15例。对照组使用鼻塞式持续气道正压通气,观察组使用湿化高流量鼻导管辅助通气,对比两组新生儿并发症发生率与撤机成功率。结果 观察组撤机失败2例,总发生率为13.33%;对照组撤机失败3例,总发生率为20.00%。组间数据对比,差异无统计学意义（P〉0.05）。与对照组相比,观察组患者的并发症的发生率较低,组间数据对比,差异具有统计学意义（P〈0.05）。结论对于呼吸衰竭新生儿,实施HHFNC进行治疗,可在保证成功撤机的前提下,降低并发症发生率。

Objective To explore the effective way of preventing extubation failure after mechanical ventilation in neonates with respiratory failure. Methods 30 cases of neonates with respiratory failure from January 2012 to September 2016 were selected as study subjects and were divided into two groups, 15 cases in each group. Control group was using by nasal continuous positive airway pressure, observation group was using by HHFNC. To compare the incidence of neonatal complications in two groups and the success rate of weaning. Results 2 cases of failure in the observation group were observed, the total incidence rate was 13.33%. Control group, 3 cases of weaning failure, the total incidence rate was 20.00%. There was no significant difference between two groups（P〈0.05）. Compared with the control group, the incidence of complications was lower in the observation group, the difference was statistically significant（P〈0.05）. Conclusion For neonatal respiratory failure, to implement HHFNC for treatment, which can guarantee the success of the withdrawal of the premise, to reduce the incidence of complications.