期刊文献+

DNA甲基化的功能以及调控机制研究

下载PDF
导出
摘要 近年来,DNA中碱基的化学修饰日渐成为生命科学领域研究的热点,因为它在生物发展过程中拥有非常特殊的功能。甲基化是一种普遍存在的修饰,它广泛分布于各种类型的DNA中,对生物的发育有着重要意义。本文简要叙述了DNA甲基化的功能,甲基化和去甲基化的机制及在肿瘤中对基因的调控作用,为认识DNA甲基化的机理和相关领域的研究提供借鉴。
机构地区 景德镇陶瓷大学
出处 《福建电脑》 2017年第1期17-18,20,共3页 Journal of Fujian Computer
基金 景德镇陶瓷大学研究生校级创新基金项目"基于SVM和伪核苷酸成份的剪接位点研究"(项目编号:JYC201521)
  • 相关文献

参考文献2

二级参考文献23

  • 1Minami N,Tsukamoto S.Role of oocyte-specific genes in the development of mammalian embryos[J].Reprod Med Biol,2006,5(3):175–182.
  • 2Assou S,Anahory T,Pantesco V,et al.The human cumulus-oocyte complex gene-expression profile[J].Hum Reprod,2006,21(7):1705–1719.
  • 3Tong Z B,Gold L,De Pol A,et al.Developmental expression and subcellular localization of mouse MATER,an oocyte-specific protein essential for early development[J].Endocrinology,2004,145(3):1427–1434.
  • 4Zeng F,Schultz R M.Gene expression in mouse oocytes and preimplantation embryos:use of suppression subtractive hybridization to identify oocyte-and embryo-specific genes[J].Biol Reprod,2003,68(1):31–39.
  • 5Thélie A,Papillier P,Pennetier S,et al.Differential regulation of abundance and deadenylation of maternal transcripts during bovine oocyte maturation in vitro and in vivo[J].BMC Dev Biol,2007,7:125.
  • 6Elis S,Batellier F,Couty I,et al.Search for the genes involved in oocyte maturation and early embryo development in the hen[J].BMC Genomics,2008,9:110.
  • 7Latham K E,Solter D,Schultz R M.Activation of a two-cell stage-specific gene following transfer of heterologous nuclei into enucleated mouse embroyos[J].Mol Reprod,1991,30:182–186.
  • 8Fitzpatrick S L,Sindoni D M,Shughrue P J,et al.Expression of growth differentiation factor-9 messenger ribonucleic acid in ovarian and nonovarian rodentand human tissues[J].Endocrinology,1998,139(5):2571–2578.
  • 9Takahashi Y,First N.In vitro development of bovine one cell embryos:influence of glucose,lactate,pyruvate,amino acids and vitamins[J].Theriogenology,1992,37:963–978.
  • 10Tong Z B,Nelson L M.A mouse gene encoding an oocyte antigen associated with autoimmune premature ovaivan failure[J].Endocrinology,1999,140(8):3720–3726.

共引文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部