核素氯化锶在治疗晚期肿瘤骨转移中的应用效果与护理体会

Application of 89SrCl2 in the treatment of advanced bone metastasis and related nursing measures

目的探讨放射性核素氯化锶注射治疗结合有效的护理干预对缓解晚期肿瘤骨转移患者疼痛的影响。方法 45例晚期肿瘤骨转移患者应用核素氯化锶静脉注射治疗,并采取相应护理措施,记录治疗后的疼痛情况及不良反应情况。结果本组治疗后出现一过性疼痛加重27例,2例服药缓解,其余均自行缓解。45例患者未发现明显骨髓抑制,发生轻度白细胞下降患者3例。治疗后Ⅰ级疼痛比例为37.8%(17/45)高于治疗前的11.1%(5/45),差异有统计学意义(P<0.01)。结论氯化锶静脉注射治疗过程中给予针对性护理,可有效减轻患者疼痛,改善生活质量。

Objective To investigate the effects of the combination of 89SrC12 injection and nursing methods on pain relief and quality of life in advanced cancer patients with bone metastases. Methods A total of 45 patients with advanced cancer with bone metastasis were treated with intrave-nous injection of 89SrC12. The corresponding nursing measures were taken. The pain degree and ad-verse reaction were observed. Results There was 27 patients with aggravated transient pain, in which 2 cases were treated by analgesic and 25 cases were relieved spontaneously. There were three cases of mild leukopenia and none of them were observed with bone marrow suppression, the proportion of pa-tients with grade I pain was 37. 8% （17/45） after treatment, which was higher than 11. 1 % （ 5/45 ） before treatment （P 〈0. 01） . Conclusion Effective nursing measures can relieve pain and improve quality of life in advanced cancer patients with bone metastasis treated with intravenous injection of 89SrC12.