颅内动脉溶栓联合机械碎栓治疗急性脑梗死的效果分析

Effect analysis of intracranial arterial thrombolysis combined with mechanical thrombectomy in the treatment of acute cerebral infarction

目的:分析颅内动脉溶栓联合机械碎栓治疗急性脑梗死的效果。方法:选取收治的50例急性脑梗死患者,分为试验组和对照组,对照组采用一般性治疗,试验组采用颅内动脉溶栓联合机械碎栓治疗,比较两组临床治疗效果。结果:对照组总有效率40.0%明显低于试验组88.0%,两组在治疗前NIHSS评分均在15~22分之间,对照组采用一般性治疗NIHSS评分为(8.07±2.86),试验组NIHSS评分为(3.34±1.98),对照组、血管再通成功率20.0%明显低于试验组血管再通成功率84.0%,对照组并发症发生率12.0%明显高于试验组4.0%,差异具有统计学意义(P<0.01)。结论:针对急性脑梗死患者采用动脉溶栓联合机械碎栓的治疗方式在严控时间窗的基础上能够有效提高临床效果,缩短再通时间,提高再通率,降低并发症发生,有利于改善患者预后,值得临床推广使用。

Objective Analysis of intracranial arterial thrombolysis combined with mechanical thrombectomy in the treatment of acute cerebral infarction. Method 50 cases of acute cerebral infarction were selected and divided into experimental and control groups,the control group received general treatment,the experimental group received intracranial arterial thrombolysis combined with mechanical thrombectomy therapy,comparison of two clinical treatment. Results The total efficiency of the control group was 40. 0%was significantly lower than 88. 0% of the experimental group,the two groups before treatment NIHSS scores were between 15 ~22 minutes,the control group with general treatment NIHSS score was（ 8. 07 ± 2. 86）,the experimental group NIHSS score was（ 3. 34 ± 1. 98）,the control group,recanalization success rate of 20. 0% was significantly lower than the experimental group recanalization success rate 84. 0%,the control group 12. 0% complication rate was significantly higher than 4. 0% in the experimental group,the difference was statistically significant（ P〈0. 01）. Conclusion For use in patients with acute cerebral arterial thrombolysis joint mechanical thrombectomy in the treatment on the basis of strictly controlling the time window can effectively improve the clinical effect and shorten the reperfusion time and improve recanalization rate and reduce complications,will help to improve the prognosis of patients,worthy of clinical use.