胃癌围手术期治疗现状和新进展

Current situation and new advances in perioperative treatment of gastric cancer

胃癌是世界上最常见的恶性肿瘤之一,手术治疗仍然是治愈胃癌的最佳方法.由于早期胃癌缺乏症状以及我国胃癌筛查不普及,我国胃癌以进展期胃癌为主.进展期胃癌单纯手术治疗效果欠佳,为了增加胃癌患者的长期生存,胃癌围手术期的综合治疗已经逐渐被广大学者所接受.胃癌围手术期治疗是综合治疗的一个重要组成部分,主要包括术前化疗、术前放化疗、靶向治疗和免疫治疗.本文就这几种综合治疗方案进行介绍.

Gastric cancer is one of the most common malignant tumors in the world, and radical surgery is still the most effective treatment. Since gastric cancer screening is not popular in China and early cases are usually asymptomatic, advanced gastric cancer accounts for the vast majority. The prognosis of patients with advanced gastric cancer after surgery alone is still poor. With regard to improving the long-term survival of patients with advanced gastric cancer, the importance of multimodality therapy has been gradually recognized. Perioperative treatment is an important part of multimodality therapy. Nowadays, the perioperative treatment for advanced gastric cancer consists of preoperative chemotherapy, preoperative chemoradiotherapy, targeted therapy, and immune therapy.