摘要
结缔组织病发病机制复杂,可有多脏器受累。Epstein-Barr病毒(Epstein-Barr virus,EBV)是全世界较为常见的一种疱疹病毒。结缔组织病与EBV之间的关联,不仅在于EBV参与结缔组织病发病,还存在EBV感染及EBV相关疾病临床表现与结缔组织病混淆的情况。本文以三种结缔组织病为例,即系统性红斑狼疮、类风湿关节炎、干燥综合征,对EBV在结缔组织病发病机制中的作用,EBV感染及EBV相关疾病诱发、模拟、并发结缔组织病进行综述。
The pathogenesis of connective tissue diseases （CTDs） is complex, and multiple organs can be in- volved. Epstein-Barr virus （EBV） is a kind of common herpes virus in the world. The associations be- tween above diseases are not only because EBV participate in the pathogenesis of CTDs, but also some- times, the clinical manifestations of EBV infection and EBV related diseases could be confused with those of CTDs. In this paper, we reviewed the role of EBV in the pathogenesis of CTDs, and EBV infection and EBV related diseases induced, simulated and accompanyed with CTDs by mainly taking three kinds of CTDs as examples, that is, systemic lupus erythematosus, rheumatoid arthritis and Sjogren syndrome.
出处
《中华临床免疫和变态反应杂志》
2016年第4期402-406,共5页
Chinese Journal of Allergy & Clinical Immunology
关键词
疱疹病毒4型
人
结缔组织病
临床关联
herpes virus 4, human
connective tissue diseases
clinical manifestations
