中、重度OSAHS患者白天嗜睡、睡眠质量及心理抑郁情况的量表分析

Application of questionnaires in the analysis of patients with moderate-severe obstructive sleep apnea ;hypopnea syndrome for daytime sleepiness,sleep at night,and psychological depression

目的：使用 Epworth 嗜睡量表（Epworth sleepiness scale,ESS）、匹兹堡睡眠质量指数（Pittsburgh sleep quality index,PSQI）及 Zung 氏抑郁自评表（Zung self-rating depression scale, ZSDS）评估中、重度 OSAHS患者受疾病影响所导致的白天嗜睡、夜晚睡眠质量及心理抑郁等情况。方法观察280例中、重度 OSAHS 患者上述3种问卷的得分及多导睡眠图（polysomnogragph, PSG）监测情况,将之与非 OSAHS的对照组人群做比较,并分析各量表之间的关系及其与 PSG指标的相关性。结果中、重度 OSAHS患者与对照组人群之间无论是日间嗜睡情况、夜间睡眠质量还是心理抑郁情况差异均有统计学意义（P〈0.05）,其中,重度 OSAHS组与对照组比较差异更为明显。ESS量表得分及ZSDS得分与呼吸暂停低通气指数存在正相关（r=0.185、0.117,P 值均〈0.05）,且3种量表两两之间呈正相关（r=0.165、0.169、0.267,P值均〈0.05）。ESS量表得分与平均氧饱和度、最低氧饱和度之间呈负相关（r=-0.214、-0.208,P值均〈0.05）,ZSDS量表得分与平均氧饱和度之间呈负相关（r=-0.172,P〈0.05）。结论中、重度 OSAHS患者的日间嗜睡、夜间睡眠质量及心理抑郁情况均较对照组严重。其中,重度 OSAHS患者更为明显。造成这一结果的原因可能与患者疾病严重程度有关,与氧饱和度下降有一定的相关性。

Objective Using Epworth sleepiness scale （ESS）, Pittsburgh sleep quality index （PSQI） and Zung self-rating depression scale （ZSDS） to assess different degree affected by the disease cause of daytime sleepiness, night sleep quality and mental depression differ in patients with moderate- severe OSAHS. Methods Survey of 280 patients＇ three questionnaire scor and PSG situation with moderate-severe OSAHS, comparing with the control group without OSAHS. Compareing the relationship between the scales and their relationship with PSG indexes. Results Moderate-severe OSAHS patients and the control group patients between three groups whether daytime sleepiness, night sleep quality and mental depression were statistical differences （ P 〈 0.05）. The severe OSAHS group compared with control group the difference is more apparent. ESS and ZSDS is positively correlated with AHI index（ r = 0. 185,0. 117, P % 0.05）, and between three questionnaire there are mutual positive correlation （r = 0. 165,0. 169,0. 267, P d0.05）. ESS questionnaire scores have a negative correlation with average oxygen saturation and the lowest oxygen saturation （ r =-0. 214, -0. 208, P % 0.05）. ZSDS questionnaire scores have a negative correlation ＇with average oxygen saturation （r =-0.172, P 〈0.05）. Conclusions With the control group, moderate-severe OSAHS patients in three groups between whether daytime sleepiness, night sleep quality and mental depression were worse. Among them severe OSAHS patients is more apparent. And the cause of this result may be associated with the severity of disease in patients with OSAHS, there is a certain correlation with oxygen desaturation.