2型糖尿病合并肌少症患者抗阻运动研究进展

Research progress of the resistance training in patients with type 2 diabetes mellitus and sarcopenia

肌少症是机体在增龄过程中出现的进行性、广泛性骨骼肌肌量、肌力及功能下降进而引起残疾、生活质量下降或死亡等不良结局的综合征。骨骼肌是人体最重要的运动器官和能量代谢组织,2型糖尿病患者由于胰岛素分泌功能受损,肌少症患病风险较高。抗阻运动是目前治疗肌少症的有效方法,相较有氧运动对血糖的控制效果更持久。本文就2型糖尿病合并肌少症的发生机制、抗阻运动的作用机制、方法及注意事项进行综述,期望为2型糖尿病合并肌少症患者提供合理有效的运动方案。

Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle and strength with a risk of adverse outcomes such as physical disability, poor quality of life and death. Skeletal muscle is the most important locomotive organ and energy metabolism organization. Patients with type 2 diabetes mellitus （ T2DM） were much likely to suffer sarcopenia due to impaired insulin secretion. Resistance training is an effective method to treat sarcopenia by far, and more it is more effectively to control the blood glucose compared with aerobic exercise. This thesis will summarize the pathogenetic mechanism of T2DM complicated with sarcopenia, and the function mechanism, methods and precautions of the resistance training, to provide reasonable and effective kinematic scheme for patients with T2DM and sarcopenia.