同步放化疗对宫颈癌患者生存质量的影响因素分析

Analysis of influence factor on the quality of life for patients with cervical cancer and undergone concurrent chemo-radiotherapy

目的:研究宫颈癌同步放化疗后影响患者生存质量的相关因素。方法:选取150例行同步放化疗的宫颈癌患者,采用调查问卷的方式,针对不同文化程度、不同经济收入、不同治疗方式以及4种临床分期等各种因素对患者生存质量的影响进行调查;采用欧洲癌症研究机构与治疗组织(EORTC)针对肿瘤患者制定的生活质量测定量表(QLQ-C30)对患者生存质量进行评分。结果:患者受教育程度和经济收入越高,临床分期越早,其生活质量越高,不同文化程度及不同收入的患者生活质量的评分比较有差异。调强放射治疗的患者优于普通放射治疗,两种治疗方法对患者生活质量的评分比较,差异有统计学意义(t=0.452,P<0.05)。结论:患者受教育程度越高,获知的宫颈癌防治知识较多,其宫颈癌的临床分期相对较早;经济收入高的患者,选择调强放射治疗的比例更大,经济收入的差异直接影响患者的营养支持,对生存质量会产生一定影响;临床分期早的患者放射治疗的范围和剂量以及化疗的次数相对会少,从而减少患者的不良反应。

Objective： To study the relative factors affecting on the quality of life for patients with cervical cancer and undergone concurrent chemo-radiotherapy. Methods： 150 patients with cervical cancer and undergone concurrent chemo-radiotherapy were chosen to investigate thequality of life by quality questionnaire table of life（QLQ-C30 EORTC）, which was formulated by the European Cancer Research Institute. The investigate content mainly included education level, economic level, therapy method and clinical stages and so on. Results： the higher education level, economic income and the earlier clinical stage can lead to higher the quality of life, and this difference is significant（P0.05）. And the quality of life was better than conventional radiotherapy if patients emphasized radiotherapy, the difference also is significant（t=0.452, P0.05）. Conclusion： patients can got more prevention and treatment knowledge about cervical cancer and easier get cure if their education level are higher. The proportion of emphasized radiation therapy is higher if patients were higher economic income; and the difference of economic income directly lead to the nutritional level of patients; and all of these factors can affect the quality of life. The range and dose of radiotherapy and chemotherapy times would decrease if patients were in early clinical stage, and this will reduce relative adverse reactions.