我院2015年住院患者抗菌药物使用强度分析

Analysis of AUD of antibacterial drugs in inpatients of our hospital in 2015

目的评价住院患者抗菌药物使用强度(AUD)情况,为抗菌药物合理使用提供依据。方法采用回顾性分析法,调取医院信息管理系统中2015年住院患者应用抗菌药物的AUD和用药频度(DDDs)进行分析。结果 2015年我院住院患者抗菌药物的使用强度为48.2,AUD排名前3的科室为重症监护病房、耳鼻喉病房和泌尿外科病房;排名前3的抗菌药物种类分别为头孢菌素类、青霉素类和硝基咪唑类,其AUD值分别为21.41、11.99、4.29;排名前3的抗菌药物为注射用头孢哌酮钠舒巴坦钠、注射用美洛西林钠和奥硝唑氯化钠注射液,其AUD值分别为11.34、4.9、4.52。结论我院抗菌药物使用强度偏高,应继续加大干预力度,促进抗菌药物的合理使用。

Objective To evaluate the antibiotics use density（AUD） in hospitalized patients,and provide basis for clinical rational use of antibacterials.Methods By retrospective study,AUD and DDDs of antibacterial drugs in inpatients of our hospital in 2015 from hospital information management system were analyzed statistically.Results The AUD of inpatients in our hospital was 48.2 in 2015.Top 3 ward in the list of AUD were ICU,otolaryngology and urology department.Top 3 types of antimicrobial agents in the list of AUD were cephalosporins,penicillins and nitroimidazoles with AUD values at 21.41,11.99 and 4.29 respectively.Top 3 antibacterial drugs in the list of AUD were cefoperazone sodium and sulbactam sodium for injection,mezlocillin sodium for injection and ornidzole and sodium chloride injection with AUD values at 11.34,4.9 and 4.52 respectively.Conclusion The AUD of our hospital is high;it is suggested to increase the intensity of intervention and to improve the rational use of antibiotics.