1例气球细胞痣临床及病理分析

Clinicopathological analysis of one case of the balloon cell nevus

目的:学习气球细胞痣的临床病理诊断及鉴别诊断。方法:对1例气球细胞痣进行临床资料、病理形态及免疫组织化学观察,并结合文献对其诊断及鉴别诊断进行学习。结果:前胸壁皮肤先天性色素痣,近1年来增大,其组织学上表现为混合痣伴多量细胞胞浆丰富,呈气球样。免疫组织化学标记气球样细胞Melan A、S100、HMB45阳性,CD68阴性。结论:气球细胞痣是较为罕见的一种黑素细胞痣,根据其临床及组织学特征,结合免疫组织化学方法,有助于其诊断及鉴别诊断。

Objective： To study the pathological diagnosis and differential diagnosis of the balloon cell nevus （BCN）. Methods： The clinical data, pathological and immunohistochemical studies of one case of balloon cell nevus were organized. And then we learned its pathological diagnosis and differential diagnosis combined with literature. Results： The congenital nevus on the skin of the chest wall was getting bigger in the past year. The performance of its histology looked as compound nevi with a large number of rich ballooning cytoplasm. The Melan A, S100, HMB45 was positive, CD68 was negative in the balloon-like cells by using immunohistochemistry. Conclusion： Balloon cell nevus is a kind of rarely melanocytic nevi. The clinical and histological features combined with immunohistochemistry of BCN can contribute to its pathological and differential diagnosis.