氨氯地平联用阿托伐他汀钙治疗高血压伴高血脂50例临床观察

目的探究氨氯地平联用阿托伐他汀钙治疗高血压伴高血脂50例临床效果，以期能够有效治疗高血压伴高血脂疾病，提升患者生活质量。方法回顾性分析2015年6月至2016年4月在本院接受治疗的高血压伴高血脂患者的临床资料，随机将其分为观察组（25例）和对照组（25例），对对照组患者行阿托伐他汀治疗，对观察组患者行阿托伐他汀联合氨氯地平治疗，对比两组患者治疗效果。结果治疗前，两组患者收缩压、血脂与舒张压差异性不明显，P〉0.05，不存在统计学意义；治疗后，观察组患者收缩压、血脂与舒张压水平得到明显改善，且与对照组患者相比，差异性较为明显，P〈0.05，存在统计学价值，观察组患者的临床治疗总有效率达到了92．0％，对照组为64．0％，两组比较差异存在统计学意义（P〈0．05）。结论研究表明，阿托伐他汀联合氨氯地平能够有效治疗高血脂伴高血压病症，强化降脂有助于提升患者身体质量，而且具有安全性与可行性，值得临床应用与推广。

Objective To explore amlodipine combined with atorvastatin calcium in the treatment of hypertension and hyperlipi- demia clinical effect in 50 cases, in order to be effective in the treatment of hypertension and hyperlipidemia disease, improve the quality of life of patients. Methods retrospective analysis of clinical data of June 2015-2016 year in April in our hospital for treatment of hy- pertension and hyperlipidemia patients and randomly divided into observation group （25 cases） and control group （25 cases）, the control group was treated with atorvastatin treatment, the observation group was treated with atorvastatin and amlodlpine treatment, treatment effects were compared between two groups. Results before treatment, two patients with systolic blood pressure. P〉0. 05 cholesterol and diastolic blood pressure difference is not obvious, there is no statistically significant ; after treatment, observation group of patients with systolic blood pressure, diastolic blood pressure and blood lipid level was significantly improved, and compared with the control group, the difference is obvious, P〈0.05, existing system Meter value, the observation group, the clinical total effective rate reached 92.0%, 64.0% in the control group, the difference between the two groups exist statistical significance （P〈0.05）. Conclusion Studies have shown that atorvastatin Amlodipine can effectively treat high cholesterol and hypertension disease, intensive lipid-lowering help to improve the quality of patient body, but also the safety and feasibility, worthy of clinical application and promotion.