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小剂量氯吡格雷对诊治高龄冠心病患者并心衰的临床研究

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摘要 目的探讨分析小剂量氯吡格雷对诊治高龄冠心病患者并心衰的临床疗效。方法2014年3月至2016年3月来我院心内科确诊的越心病患者84例,随机将其分为三组,对照组,观察1组和观察2组,每组各28例。对照组患者采用阿司匹林治疗,观察1组在对照组治疗的基础上进行小剂量氯吡格雷治疗,观察2组在对照组治疗的基础上加用大量氯吡格雷治疗。观察三组患者用药后的临床疗效,左心射血分数,每搏输出量,心电图ST-T变化及不良反应的发生率。结果三组患者经过药物治疗后,用药临床疗效比较,差异显著,有统计学意义(P〈0.05);对照组与观察两组心电图结果比较,差异显著,有统计学意义(P〈0.05);对照组与观察1组、观察2组心绞痛缓解时间比较,差异显著,有统计学意义(P〈0.05),而观察1组与观察2组比较,差异不显著,无统计学意义(P〈0.05)。结论阿司匹林联合氯吡格雷使用治疗高龄冠心病效果较好,且小剂量的氯吡格雷对于高龄冠心病患者的治疗更佳,使用更加安全,值得在临床上进行推广。
作者 张卫卫 蔡琴
出处 《检验医学》 CAS 2016年第B09期298-299,共2页 Laboratory Medicine
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