摘要
The histopathological features of the middle cerebral artery(MCA) and superficial temporal artery(STA) from moyamoya disease(MMD) and their relationships with gender,age,angiography stage were explored.The causes and the clinical significance of vasculopathy of STA were also discussed.The clinical data and specimens of MCA and STA from 30 MMD patients were collected.Twelve samples of MCA and STA from non-MMD patients served as control group.Histopathological examination was then performed by measuring the thickness of intima and media,and statistical analysis was conducted.The MCA and STA specimens from MMD group had apparently thicker intima and thinner media than those from the control group.There was no significant pathological difference between the hemorrhage group and non-hemorrhage group,and between the males and females in MMD patients.Neither the age nor the digital subtraction angiography(DSA) stage was correlated with the thickness of intima in MCA and STA.MMD is a systemic vascular disease involving both intracranial and extracranial vessels.Preoperative external carotid arteriography,especially super-selective arteriography of the STA,benefits the selection of donor vessel.
The histopathological features of the middle cerebral artery(MCA) and superficial temporal artery(STA) from moyamoya disease(MMD) and their relationships with gender,age,angiography stage were explored.The causes and the clinical significance of vasculopathy of STA were also discussed.The clinical data and specimens of MCA and STA from 30 MMD patients were collected.Twelve samples of MCA and STA from non-MMD patients served as control group.Histopathological examination was then performed by measuring the thickness of intima and media,and statistical analysis was conducted.The MCA and STA specimens from MMD group had apparently thicker intima and thinner media than those from the control group.There was no significant pathological difference between the hemorrhage group and non-hemorrhage group,and between the males and females in MMD patients.Neither the age nor the digital subtraction angiography(DSA) stage was correlated with the thickness of intima in MCA and STA.MMD is a systemic vascular disease involving both intracranial and extracranial vessels.Preoperative external carotid arteriography,especially super-selective arteriography of the STA,benefits the selection of donor vessel.
作者
孙守家
章剑剑
李正伟
熊忠伟
吴小林
王胜
舒凯
陈劲草
Shou-jia SUN Jian-jian ZHANG Zheng-wei LI Zhong-wei XIONG Xiao-lin WU Sheng WANG Kai SHU Jin-cao CHEN(Department ofNeurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China Department of Neurosurgery, Zhongnan Hospital Wuhan University, Wuhan 430071, China)
基金
supported by the key project of the Natural Science Foundation of Hubei Province of China(No.ZRZ2014000254)
the National Natural Science Foundation of China(No.81571146)