摘要
目的:探讨年龄因素对腹部手术后急性胰岛素抵抗发生的影响。方法:选取我院实施腹部手术的60例患者,分为2组:年龄>60岁为老年组(S组),年龄<50岁为青年组(Y组)。测定患者术前,手术后6h、12h、24h、72h血糖,血胰岛素以及过氧化物酶歧化酶(SOD)、丙二醛(MDA)水平,计算胰岛素抵抗指数(HOMA-IR)。结果:S组患者腹部手术后HOMA-IR较Y组显著增高,同时MDA水平上升,SOD水平下降。结论:年龄是腹部手术后出现急性胰岛素抵抗的一个重要因素,其发生可能与老年患者氧化应激过强有关。
Objective：To investigate the influence of age factor on the occurrence of acute insulin resistance for abdominal surgery patients.Method：Sixty cases of patients undergoing abdominal surgery were divided into two groups.senior group and young group.Blood sugar,insulin SOD and MDA were measured in five time points,preoperation,6h,12 h,24hand 72 hpost operation.Homeostasis model assessment insulin resistance（HOMA-IR）was calculated.Result：HOMA-IR and serum MDA were significantly higher and SOD was lower in senior group than young group at time points post operation.Conclusion：Age is an important factor for the occurrence of acute insulin resistance post abdominal operation.Oxidative stress may play a role in it.
出处
《临床急诊杂志》
CAS
2016年第12期927-929,共3页
Journal of Clinical Emergency
关键词
腹部手术
胰岛素抵抗
氧化应激
年龄
abdominal surgery
insulin resistance
oxidative stress
age
