盐酸替罗非班在ST段抬高急性心肌梗死治疗的临床应用

Clinical application of the treatment of ST segment elevation acute myocardial infarction in patients with acute myocardial infarction

目的:研究盐酸替罗非班在ST段抬高急性心肌梗死(STEMI)治疗的临床应用疗效。方法:选取南通市通州区人民医院和上海市第一人民医院共收治的80例接受急诊经皮冠状动脉介入治疗(PCI)的STEMI患者作为观察对象,随机分为对照组与治疗组。对照组给予肝素、阿司匹林、氯吡格雷治疗,治疗组则在对照组的基础上联合实施盐酸替罗非班治疗。记录2组患者的手术一般情况,统计2组患者在住院期间与住院之后心脏不良事件(MACE)的发生率。结果:治疗组术后的临床疗效明显优于对照组(P<0.05),治疗组的MACE发生率大于对照组。结论:针对STEMI行PCI治疗的患者,对其采用盐酸替罗非班治疗,能够显著提高患者的临床疗效,对其治疗过程中出现的不良反应加以监测与采取相应的治疗,症状均可缓解。

Objective：To study the hydrochloric acid for class had in st-elevation acute myocardial infarction（STEMI）treatment of clinical curative effect.Method：Shanghai first people＇s hospital treated 80 cases accepted emergency percutaneous coronary intervention（PCI）in patients with STEMI as research object,the 2groups were randomly divided into control group and treatment group,control group given heparin,aspirin and clopidogrel treatment,the treatment group is in the control group on the basis of joint implementation of hydrochloric acid for class had treatment.Operation record 2groups of patients in general situation,the statistics of 2groups of patients during hospitalization and after hospitalization incidence of adverse cardiac events（MACE）.Result：The postoperative clinical curative effect of treatment group was obviously better than the control group（P〈0.05）,the treatment group the incidence of MACE is greater than the control group.Conclusion：Patients treated for line STEMI PCI,the class had treatment for using hydrochloric acid,can significantly improve the patient＇s clinical curative effect,in the process of the treatment of adverse reactions to monitoring and taking corresponding treatment,the symptoms can alleviate.