麦门冬汤治疗抗抑郁药胃肠道副反应属肺胃阴虚型32例疗效观察

Clinical Observation of Maimen Dong Decoction in Treating 32 cases of Defi ciency of Both Lung and Stomach Yin Type Gastrointestinal Side Effects Caused by Antidepressant

目的:观察麦门冬汤加减治疗抗抑郁药物所致胃肠道副反应辨证属肺胃阴虚型的临床疗效。方法:将64例抗抑郁药物所致胃肠道副反应的患者按照收治顺序单双号分为2组,单号治疗组32例予麦门冬汤加减治疗,双号对照组32例予吗丁啉治疗,2组均以2周为1个疗程,连续治疗2个疗程后评价疗效。结果:治疗组有效率84.38%;对照组有效率68.75%(P<0.05),治疗组与对照组疗效有显著差异。结论:麦门冬汤治疗抗抑郁药物所致胃肠道副反应辨证属肺胃阴虚型的效果良好,值得临床加以推广运用。

Objective： To observe the clinical effect of Maimendong decoction on treating gastrointestinal side effect caused by antidepressant. Methods： 64 cases of gastrointestinal side effects caused by antidepressant drugs were divided into two groups according to the order of treatment. The single treatment group（32 cases） was treated with Maimen Dong Decoction, and the control group（32 cases） Butanol treatment. One course of treatment in each group was 2 weeks, and the curative effect was evaluated after two courses of continuous treatment. Results： The total effective rate in the treatment group was 84.38%; the total effective rate in the control group was 68.75%（P 0.05）. There was significant difference between the treatment group and the control group. Conclusion： Maimen Dong decoction in treating deficiency of both lung and stomach yin type gastrointestinal side effects caused by antidepressant show a good effect. It is worthy to be popularized in clinical practice.