卡前列素氨丁三醇预防双胎产后出血的临床分析

Clinical Analysis of Carboprost Tromethamine in Prevention of Postpartum Hemorrhage with Twin Pregnancy

目的:观察和分析卡前列素氨丁三醇预防双胎产后出血的临床疗效。方法:选取210例双胎妊娠产妇作为研究对象,并将其随机分为治疗组和对照组,每组105例。治疗组使用卡前列素氨丁三醇,对照组使用缩宫素。分析比较两组产后24 h出血量和出血发生率。结果:治疗组的产后出血量明显少于对照组,差异具有统计学意义(t=8.52,P<0.01)。治疗组产后出血的发生率为7.6%,对照组产后出血的发生率21.0%,差异有统计学意义(P<0.01)。治疗组的不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论:卡前列素氨丁三醇预防双胎产后出血临床疗效显著,可有效降低产后出血发生率。

Objective To observe and analyze the clinical effect of carboprost tromethamine in prevention of postpartum hemorrhage with twin pregnancy. Method 210 cases of twin pregnant were selected as the research subjects and were randomly divided into treatment group and control group, 105 cases in each group. Carboprost trometharninel was used in the treatment group, and the control group was treated with oxytocin. Analysis and comparison of maternal postpartum 24 h bleeding and bleeding incidence. Results The amount of postpartum hemorrhage in the treatment group was significantly less than that of the control group, with significant difference （ t = 8.52,P 〈 0.01 ）. The postpartum hemorrhage rate of treatment group was 7.6% ,the control group was 21.0% ,the diferernee between the two groups was statistically significant （P 〈 0. 01 ）.The incidence of adverse reactions of the treatment group was significantly lower than control group,the difference was statistically significant （P 〈 0. 05 ）. Conclusion The clinical effect of carboprost tromethamine in prevention of postpartum hemorrhage with twin pregnancy is remarkablet,which can effectively reduce the incidence of postpartum hemorrhage.