嗜铬细胞瘤与副神经节瘤的临床诊断进展

Clinical diagnosis of pheochromocytoma and paraganglioma

嗜铬细胞瘤(PHEOs)是肾上腺髓质嗜铬细胞恶性增生形成的罕见的神经内分泌肿瘤。副神经节瘤(PGLs),即肾上腺外嗜铬细胞瘤,与嗜铬细胞瘤一样,可大量分泌儿茶酚胺及其代谢产物。虽然自20世纪初以来对于这些肿瘤一直都有所认识,但是PHEO/PGLs领域的许多新进展已经从根本上改变了对这类肿瘤的理解,该文综述了PHEO/PGLs诊断领域的临床现状与进展。

Pheochromocytomas（PHEOs）which are rare neuroendocrine tumors in adrenal medulla and paragangliomas（PGLs）which are extraadrenal pheochromocytomas,cause a large number of catecholamine and its metabolites. Since the beginning of the 20 th century,these tumors have always been known,but new developments have fundamentally changed the understanding of this kind of tumor. This article reviews the clinical diagnosis and progression in PHEO/PGLs.